Oseltamivir is an antiviral drug, a neuraminidase inhibitor used
in the treatment of and prophylaxis of both influenza A and influenza B.
Oseltamivir was the first orally active neuraminidase inhibitor commercially
developed. It was developed by Gilead Sciences and is currently marketed by
Hoffman La Roche (Roche) under the trade name TamifluŽ.
Oseltamivir is a prodrug, usually administered as oseltamivir phosphate, with
the drug being converted hepatically to the active metabolite GS4071 in vivo.
Like zanamivir, oseltamivir acts as a transition-state analogue inhibitor of
influenza neuraminidase.
On March 1st 2005, the U.K. government announced that it would be stockpiling
enough oseltamivir to treat a quarter of the country's population,
in
preparation for a possible H5N1 avian flu pandemic.
However, stockpiles will
probably dwindle quickly in case of a pandemic outbreak. Toward the end of
May 2005 Roche Holding AG confirmed that huge demand for TamifluŽ was causing a
production bottleneck, with new customers likely to face waiting time of up to
two years.
In order to satisfy U.S. demand, Roche planned to open a new production plant in
North America during the second half of 2005.
Tamiflu also appears to be active against canine parvovirus, feline
panleukopenia, and the canine respiratory complex known as "kennel cough."
Veterinary investigation of this is ongoing, but many shelters and rescue
groups have reported great success employing Tamiflu in the early stages of
these illnesses.
Kimchi Recipe: Easy Korean Recipe
The source of this article is
Wikipedia, the free encyclopedia. The text of this
article is licensed under the
GFDL
Post nasal drip, lose weight, diabetes, Alzheimer's, more
how to clean athletic shoes, get rid of roaches
Guides for Better LivingHow to Cope with Life's Problems
*This
site does not provide medical advice.
The contents of this site, such as text, graphics, images, information and other
material ("Content") contained on the this site, is for information purposes
only. The Content is not intended to be a substitute for professional medical
advice, diagnosis or treatment (and the Site does not render medical, nursing,
or professional health-care advice in any jurisdiction). Always seek the advice
of your physician or other qualified health provider with any questions you may
have regarding a medical condition or medical treatment. Never disregard
professional medical advice or delay in seeking it because of something you have
read on this Site.
If you think you may have a medical emergency, call your doctor, or 911 or other
emergency service number immediately. Our site does not recommend or endorse any
specific tests, products, procedures, opinions or other information that may be
mentioned on the Site. Reliance on any information provided by this Site is
solely at your own risk.